Ultrafast Comparison of Personal Genomes via Precomputed Genome Fingerprints

Ultrafast Comparison of Personal Genomes via Precomputed Genome Fingerprints

We present an ultrafast method for comparing personal genomes. We transform the standard genome representation (lists of variants relative to a reference) into "genome fingerprints" via locality sensitive hashing. The resulting genome fingerprints can be meaningfully compared even when the input data were obtained using different sequencing technologies, processed using different pipelines, rep...

Personal genomes in progress: from the Human Genome Project to the Personal Genome Project

The cost of a diploid human genome sequence has dropped from about $70M to $2000 since 2007--even as the standards for redundancy have increased from 7x to 40x in order to improve call rates. Coupled with the low return on investment for common single-nucleotide polylmorphisms, this has caused a significant rise in interest in correlating genome sequences with comprehensive environmental and tr...

Ethnically relevant consensus Korean reference genome towards personal reference genomes

Personal phenotypes to go with personal genomes

This is an open-access article distributedunder the terms of theCreativeCommonsAttribution Licence,which permits distribution and reproduction in any medium, provided the original author and source are credited. Creation of derivative works is permitted but the resulting work may be distributed only under the same or similar licence to this one. This licence does not permit commercial exploitat...

Integrating Faces and Fingerprints for Personal Identiication

An automatic personal identiication system based solely on ngerprints or faces is often not able to meet the system performance requirements. Face recognition is fast but not reliable while ngerprint veriication is reliable but ineecient in database retrieval. We have developed a prototype biometric system which integrates faces and ngerprints. The system overcomes the limitations of face recog...